Best Capillary Electrophoresis Systems for Pharmaceutical and Biopharmaceutical Laboratories

Key Points

• Choose the capillary electrophoresis system from the assay and data workflow, not from a single throughput or resolution claim. CE-SDS, cIEF or icIEF, capillary zone electrophoresis, small-molecule CE, and CE-MS place different demands on hardware, detection, consumables, and software.
• SCIEX PA 800 Plus is the strongest overall choice when a laboratory needs flexible, established biopharmaceutical assays and a practical path from development into controlled quality workflows.
• SCIEX BioPhase 8800 is the throughput leader in this comparison because eight capillaries run in parallel, while Bio-Techne Maurice is the most streamlined option for routine protein size and charge analysis.
• Agilent 7100 CE is the broadest general-purpose platform and the strongest fit when the laboratory needs multiple CE modes or CE-MS rather than a primarily kit-based biologics workflow.
• No instrument or software package makes a laboratory compliant by itself. Validation, access governance, audit-trail review, method control, training, backup, and record retention remain laboratory responsibilities.