Press release summary
Quantum-Si has reported interim development data comparing its forthcoming Proteus protein-sequencing platform with the company’s commercial Platinum Pro instrument.
Using a developmental kit that detects 18 amino acids, a single Proteus chamber produced a median 30 times more alignments in a control-peptide study, identified all six control peptides in every run, and recorded a median false discovery rate of 1.36%, compared with 6.58% for Platinum Pro. In protein-mixture experiments, Proteus identified 1.6 to 2 times more peptides. It detected all 24 proteins in a separate panel and 4.3 times more amino acids per run, according to the company.
Quantum-Si projected that a four-chamber Proteus run could produce about 60 times more alignments than a two-chamber Platinum Pro run. That figure is a projection, not a measured full-run result. The instrument, consumable, loading protocol, and analysis software remain in development.
Why it matters for laboratories
The data suggest a possible increase in throughput and sequence coverage for benchtop single-molecule protein analysis. Laboratories should view the results as preliminary company data until the platform is fully optimized, independently evaluated, and commercially available.
Original source: Quantum-Si release, Sept. 28, 2026.
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